Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v)
نویسندگان
چکیده
منابع مشابه
Pandemic (H1N1) 2009 influenza.
On 11 June 2009, the World Health Organization declared the first human influenza pandemic since 1968–1969. The responsible virus, pandemic (H1N1) 2009 influenza, is a novel triple-reassortant influenza A virus, incorporating avian, swine and human influenza genes.1 The virus is resistant to the anti-influenza medications, amantadine and rimantadine, but is generally sensitive to the neuraminid...
متن کاملAmantadine-Resistant among Seasonal H1N1 and 2009 Pandemic Isolated of Influenza A Viruses in Iran
Background and Aims: Influenza A viruses are important pathogens for humans especially in pandemic episodes. Two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza A virus infections. However, single amino acid substitutions in the M2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...
متن کاملCharacterization of Oseltamivir-Resistant 2009 H1N1 Pandemic Influenza A Viruses
Influenza viruses resistant to antiviral drugs emerge frequently. Not surprisingly, the widespread treatment in many countries of patients infected with 2009 pandemic influenza A (H1N1) viruses with the neuraminidase (NA) inhibitors oseltamivir and zanamivir has led to the emergence of pandemic strains resistant to these drugs. Sporadic cases of pandemic influenza have been associated with muta...
متن کاملEvolutionary pattern of pandemic influenza (H1N1) 2009 virus in the late phases of the 2009 pandemic.
Influenza A( H1N1)v has spread rapidly in all parts of the globe in 2009 as a true pandemic, although fortunately a clinically mild one. The relevant evolutionary steps for the new virus to adapt to human populations occurred very early during the pandemic, before the end of April. Of the several resulting clades or clusters, clade 7 appeared later and proved more successful, substituting all o...
متن کاملEvolutionary pattern of pandemic influenza (H1N1) 2009 virus in the late phases of the 2009 pandemic. Œ PLOS Currents Influenza
Influenza A(H1N1)v has spread rapidly in all parts of the globe in 2009 as a true pandemic, although fortunately a clinically mild one. The relevant evolutionary steps for the new virus to adapt to human populations occurred very early during the pandemic, before the end of April. Of the several resulting clades or clusters, clade 7 appeared later and proved more successful, substituting all ot...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2011
ISSN: 1743-422X
DOI: 10.1186/1743-422x-8-250